Maniac is often an inaccurate and discriminatory term for a mentally ill person. Psychosis is a complex type of mental disorder, and its causes include genetic factors, neurobiological factors, psychosocial factors, environmental factors, and autoimmune factors.

1. Genetic factors: Variants or genetic mutations in certain genes may increase the risk of psychosis. For example, schizophrenia has a higher genetic predisposition in some families.

2. 神經生物學因素：大腦結構和功能的異常，神經遞質（如多巴胺、5-羥色胺等）的失衡，可能導致精神病的發生。

3. Psychosocial factors: Long-term psychological stress, major life events (such as the death of a loved one, unemployment, etc.), childhood trauma, etc., may cause mental problems.

4. Environmental factors: Poor living conditions, such as poverty, violence, social isolation, etc., can increase the incidence of mental illness.

5. Autoimmune factors: Abnormalities in the immune system may attack the nervous system, which can trigger mental disorders.

In conclusion, the occurrence of psychosis is the result of a combination of factors. For patients with mental illness, they should be given understanding, care and support, seek professional medical help in a timely manner, and promote recovery and improve their quality of life through comprehensive methods such as medication and psychotherapy.

This article is only for health science popularization and does not constitute medication or medical guidelines, it is recommended to seek medical attention in time if you have health problems.