Lao Ma is particularly fond of health preservation, but he does not believe in health products sold in pharmacies, but has a soft spot for traditional Chinese medicine. In addition to going to the Chinese medicine clinic to prescribe prescriptions, Lao Ma will also go to his hometown to dig up Chinese medicinal materials in the mountains, and drink a bowl of homemade Chinese medicine almost every day. He always said to people: "The things left by this ancestor are not harmful to people, Chinese medicine is healthy, and longevity is prolonged." ”

However, my friend Uncle Kun didn't think so: "It's a three-point poison, I heard that Chinese medicine is nephrotoxic, if you eat it like this, you will eat yourself out of illness sooner or later." Everything is about moderation, I think you better take it easy, don't give yourself a kidney cancer. ”

As a unique drug used in TCM for the prevention and treatment of diseases, traditional Chinese medicine is increasingly used in the treatment of a variety of diseases. However, at the same time, more and more studies have pointed out that improper use of traditional Chinese medicine can increase the possibility of renal impairment in patients.

1. Can I get kidney cancer if I eat too much Chinese medicine?

Modern toxicology has shown thatIn the process of clinical use, traditional Chinese medicine can cause toxic reactions to the kidneys, which is nephrotoxic.Some Chinese medicinesContains toxic components, which can be transported from the exposed site to the target site, react with the target molecule, and cause abnormal kidney cell structure and function, thereby inducing kidney damage.

The kidneys mainly excrete drug metabolites from the body through the filtration of glomeruli to maintain the stable state of the body. As a result, if the human body does not excrete the drug from the body in time when taking Chinese medicine, it can easily lead to kidney damage.

Current studies have shown that the traditional Chinese medicine such as Mutong, Magnolia, Fentuo, and Asarum can lead to kidney failure if taken for a long time. thereintoMulberry acid quiltIt is thought to have obvious nephrotoxicity, which can cause impaired renal tubular function and even have the risk of kidney cancer.

Aristolochic acid is a common component of Aristolochiaceae plants and is a nitrophenanthrene derivative. Chinese herbal medicineAristolochia, Guan Mu Tong, Guang Fangji, Magnolia, Aoki Xiang and Tianxian Vineand other drugs have a higher content of aristolochic acid. Among the Chinese patent medicines, the content of manna disinfection pills, gentian laxative liver pills, paishi granules, paishi decoction, angelica sinensis decoction, and guanxin suhe pills are relatively high.

Research has shown thatAcute and chronic renal tubulointerstitial disease and urinary system tumors caused by aristolochic acid are irreversibleIt was known as Chinese herbal nephropathy, which was later renamed aristolochic acid nephropathy.

Therefore, although it is too absolute to say that "taking too much Chinese medicine will cause kidney cancer", we need to understand the toxic and side effects in advance, and we must have a correct concept of taking medicine, so as not to backfire.

Traditional Chinese medicine has a therapeutic effect, but at the same time toxic side effects, most of the drugs are metabolized through the liver and kidney, if the abuse of traditional Chinese medicine, it will definitely greatly increase the burden on the liver and kidney.

It is actually a very dangerous behavior for ordinary people to take Chinese medicine as a daily health care product without authorization. Of course, the above explanation is not to completely distanquench everyone from Chinese medicine. Generally speakingUnder the premise of closely monitoring urine and kidney function indicators, TCM treatment can be carried out safely, but when taking TCM daily, it is necessary to follow the doctor's instructions and not blindly take it.

In addition, we should have a correct understanding of traditional Chinese medicine, whether it is "traditional Chinese medicine is safe and non-toxic" or "traditional Chinese medicine has great toxic side effects and cannot be used", it is biased. It is not advisable to take Chinese medicine in large doses or for a long time in daily life. The prescription prescribed by the doctor should be kept well, so that it is easy to quickly trace the source and find out the cause once there is a problem.

2. Kidney cancer is increasing, who is to blame?

Kidney cancer, also known as renal cell carcinoma and renal gland cancer, originates from the urinary tubular epithelium, is one of the most common malignant tumors of the urinary system, and is also one of the top ten most common cancers in men in China today.

Studies have shown that the cumulative incidence of kidney cancer in China has doubled in the past 20 years. Once symptoms of kidney cancer appear, it is often at an advanced stage, affecting life expectancy and quality of life.

In addition to the above-mentioned Chinese medicine nephrotoxicity may induce kidney cancer, 5 common bad habits in daily life, if "persistent" for a long time, will cause a lot of damage to the kidneys, and it is easy to induce kidney cancer"Help”。

1. Obesity

Currently, obesity has become the leading cause of kidney damage. A large number of studies have shown that the mechanism of kidney injury caused by obesity may be related to factors such as renal remodeling, hyperinsulinemia, hyperleptinemia, hyperlipidemia and essential hypertension. These factors are involved in the onset and progression of kidney damage and make the kidneys more susceptible to carcinogens.

2. Eating too much

Sodium and water retention and high blood pressure from a high-salt diet can lead to a state of "high stress, high perfusion, and high filtration" in the glomeruli, thus increasing the burden on the kidneys. In addition, a long-term high-salt diet can also lead to an increase in urinary calcium, which increases the risk of kidney stones.

3. Drinking too little water

The urine output of a normal person is about 2000-0ml/day, and the amount of water should be kept at about 0-0ml per day.If you don't drink enough water for a long time and like to hold urine, it can easily lead to urinary tract infections and nephritis, and repeated attacks can lead to chronic infections and may also develop into uremia.The common clinical kidney stones and hydronephrosis are also closely related to holding urine for a long time and not drinking water.

4. Staying up too late

中醫認為，腎最脆弱的時間是晚上23時～淩晨1時。因此長期熬夜通宵，特別是不睡“子午覺”的人，很容易損傷腎臟，因此建議保持良好的作息習慣。

5. Excessive use of drugs

The kidneys are important organs for drug metabolism and excretion, and improper use of drugs or the body's sensitivity to drugs will damage the kidneys.About 25% of patients with renal failure are related to the nephrotoxicity of the drug.In particular, sulfonamides, quinolones, contrast agents, and aminoglycoside antibiotics are more likely to cause kidney damage.

3. If there are 6 symptoms, or the kidneys are "calling for help"

Many patients do not pay attention to the signals sent by the kidneys in the early stage, and often go to the hospital for examination when the kidney damage has progressed to the middle and advanced stages, which poses a greater threat to the health and life of the patients. When there is a problem with the kidneys, it usually gives us the following 6 signals:

Abnormal urine output:abnormally high or low urine output,Nocturia is markedly increasedIn many cases, you should go to the nephrology department for examination in time.

Abnormal urine color and condition:If protein leaks from the kidneys into the urine, the urine will foam a lot. In addition, when urinalysis shows protein or red blood cells, it is likely to be a sign of kidney disease and requires further testing.

Dropsy:Patients with chronic kidney disease due to the decline of renal excretion, the hormone secretion disorder of the kidneys and the loss of urine protein,Sodium and water retention occurs, resulting in edema of the eyelids and lower extremities.

Hypertension:Disturbances in the renal circadian clock can alter the blood pressure rhythm in patients with chronic kidney disease, resulting in:Blood pressure rises at night, which manifests as "non-spoon blood pressure". Non-spoon blood pressure keeps the glomeruli hyperfiltered at night, which in turn accelerates the progression of kidney disease.

Gastrointestinal upset:Many people with kidney disease develop it due to toxin retentionLoss of appetite, nausea and vomitingand other symptoms. So in this case, in addition to digestive problems, you should also pay attention to whether there is something wrong with the kidneys.

Anaemia:In addition to the function of excreting waste, the kidneys can also secrete erythropoietin and promote hematopoiesis, so anemia is also a major signal of kidney damage.

Ren Jian, Deputy Chief Physician of the Department of Urology, China-Japan Friendship HospitalIt is pointed out that prevention is better than cure of kidney cancer. To maintain kidney health, first and foremostQuit bad habitsFor example, quit smoking and limit alcohol, eat less fried food or food with strong taste, do not abuse painkillers, etc., reduce exposure to harmful chemicals and less contact with radiated items, etc., and stay away from risk factors as much as possible.

At the same time, it is necessary to do a good jobRegular health check-ups。 Tests such as urinalysis and renal function tests can determine the "working" status of the kidneys and help detect lesions early. In addition, to:Emphasis is placed on early prevention and active treatment of underlying chronic diseases.Patients with hypertension and diabetes should strictly control their blood pressure and blood sugar to meet the target, and stay away from risk factors that may cause chronic kidney disease. Finally, once kidney damage is found, seek medical attention immediately, diagnose it in time, and treat it early.

In summary, kidney disease should not be underestimated, it has a complex cause, and once obvious symptoms appear, it often means that the disease has progressed to a more serious level. Therefore, people must have an in-depth understanding of kidney problems in their lives and actively take effective preventive measures.

參考資料:

[20] Analysis of the causes of clinical misdiagnosis of chronic renal insufficiency. Clinical misdiagnosis and mistreatment.0-0-0

[24] "Improper medication can lead to kidney failure". Popular Science and Technology News. 0-0-0

[09] "Which Diseases Are Sneaking Up on Your Kidneys". CBN Daily.0-0-0

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