When you feel slightly unwell, do you choose to go to the hospital immediately or endure it first? Some people feel that it is very troublesome to go to the hospital to see a doctor, and a minor problem may be cured after a while. However, the doctor reminds that if these 10 diseases are left untreated and not treated in time, the probability of long-term cancer will be greatly increased!

1. Chronic atrophic gastritis → gastric cancer

Sheng Wang, deputy chief physician of the Department of Medical Oncology of the First Affiliated Hospital of Xiamen University, published an article on the hospital's WeChat official account in 10 years and 0 to introduce the general development process of gastric cancer: normal gastric mucosa→ chronic superficial gastritis→ chronic atrophic gastritis→ intestinal metaplasia, dysplasia, → gastric cancer.

Chronic atrophic gastritis does not necessarily progress to stomach cancer, but if it is left unattended and repeatedly stimulated, such as heavy drinking, bile reflux, Helicobacter pylori or long-term use of some special drugs, it may become cancerous.

2. Adenomatous gut polyps → gut cancers

Dr Sheng Wang said that studies have shown that the vast majority of bowel cancers are caused by intestinal polyps. There are many types of intestinal polyps, among them, adenomatous polyps are recognized as precancerous lesions, especially those with a diameter of 2 cm, with a high probability of cancer, and the cancerous process is: small polyps→ adenomas→ high-grade neoplasia→ colorectal cancer.

However, it generally takes 10~0 years from benign polyps to cancer, and at this stage, as long as polyps are found, even small adenomas can be removed in time, the risk of bowel cancer can be reduced.

3. Breast atypical hyperplasia → breast cancer

Dr. Sheng Wang pointed out that the development process of breast cancer has the following 4 steps: hyperplasia→ atypical hyperplasia→ carcinoma in situ → invasive carcinoma. Most women have physiological growths that do not become cancerous. But if it is written on the report sheet that it is atypical, you should pay attention.

Atypical hyperplasia is an intermediate station from benign to malignant changes, and if you have atypical hyperplasia of the breast lobule or ductal epithelium, the risk of breast cancer is 18~0 times that of normal women.

4. Viral hepatitis → liver cancer

解放軍總醫院第二醫學中心保健五科副主任醫師郭萬峰2024年11月在騰訊醫典微信公號刊文介紹，病毒性肝炎、脂肪肝和酒精肝等都可能增加罹患肝癌的風險。慢性病毒性肝炎是導致肝癌的重要原因之一。

The hepatitis virus continues to replicate in the liver, causing chronic damage to the liver, and if left untreated, it can develop into cirrhosis, which can become liver cancer if it progresses further.

5. Chronic pancreatitis → pancreatic cancer

According to Dr. Guo Wanfeng, some bad lifestyle habits, such as overeating and excessive drinking, will increase the secretion of pancreatic juice, causing local stimulation of the pancreas and inflammatory reactions.

Pancreatitis is divided into acute and chronic. Acute pancreatitis is a dangerous attack that can lead to infection and organ failure and death. Chronic pancreatitis, in the case of poor control, will cause irreversible damage to the pancreas and evolve into pancreatic cancer.

6. Gallstones → gallbladder cancer

Tang Shengli, deputy chief physician of the Department of Hepatobiliary and Pancreatic Surgery of Zhongnan Hospital of Wuhan University, published an article on the hospital's WeChat official account in 2023 years, proposing that regardless of the size of the stone and whether there are symptoms, gallstones should be intervened and treated as soon as possible.

Generally, stones with a diameter of 5~0 mm will be stuck in the common bile duct and cause cholangitis, and even acute obstructive purulent cholangitis and pancreatitis, which will be life-threatening. Stones with larger diameters, such as stones of 0~0 mm, are easy to "block" in the "outlet" of the gallbladder (the neck of the gallbladder), resulting in the gradual atrophy of the gallbladder, which becomes a factor that induces cancer.

7. Long-term bladder infection → bladder cancer

Pan Li, the first ward of abdominal radiotherapy of Sichuan Provincial Cancer Hospital, pointed out in an article published on the hospital's WeChat official account in 11 years and 0 that long-term chronic bladder irritation, such as infection, stones, urinary tract obstruction and other diseases, can cause precancerous lesions in the bladder mucosa. If severe mucosal dysplasia, glandular cystitis, and leukoplakia are left untreated, bladder cancer may develop.

8. Chronic prostate inflammation → prostate cancer

Pan Zhanhe, chief physician of the Department of Medical Oncology of Zhongshan Hospital Affiliated to Xiamen University, pointed out in an article published on his personal WeChat account in 8 years and 0 that long-term chronic inflammation of the prostate can lead to excessive cell proliferation to repair diseased tissues, which is easy to form infection-related cancers. Epidemiological studies have shown that patients with a history of sexually transmitted diseases or prostatitis have a significantly increased risk of prostate cancer.

9. Cervical intraepithelial lesions → cervical cancer

四川省成都市婦女兒童中心醫院病理科副主任醫師蔡健2023年在醫院微信公號刊文指出，宮頸上皮細胞在HPV（人乳頭瘤病毒）持續感染後，可從發生非典型增生再轉變為宮頸癌。宮頸高級別鱗狀上皮內病變被認為是宮頸鱗癌的癌前病變。這意味著如果不及時干預和治療，有可能進一步發展為宮頸癌。因此，一定要及時就醫進行進一步的檢查和治療。

10. Hand-foot junction nevus → melanoma

Dr. Cai Jian said that junctional nevi mostly grow in the palms, plantar feet, outside and other areas that are easy to rub, and have a high probability of becoming cancerous compared with other moles.

If you notice that the mole has an irregular shape, blurred borders, different shades of color, blurring or slowly increasing in size, and a slight bulge or thickening of the skin, it is necessary to see a doctor in time.