快科技3月28日消息，據報導，美國哥倫比亞大學和法國波爾多大學科學家在3月26日《自然》雜誌發表重大研究成果，成功繪製全球首張人腦能量分布圖MitoBrainMap。

This breakthrough provides an important basis for studying the pathogenesis of neurodegenerative diseases such as Alzheimer's disease and psychiatric diseases such as depression and developing new therapies.

The research team cut frozen human brain tissue into 3 0 x 0×0 mm cubes (about the size of a grain of sand).Biochemical and molecular techniques were used to determine the mitochondrial density and productivity efficiency of each sample, and then the local data were extrapolated to the whole brain through computer modeling, and finally the map was completed.

The study found that there were significant regional differences in the distribution of mitochondria in the human brain: the number of mitochondria in gray matter was more than 50% higher than that in white matter and the production efficiency was higher, while the specific brain region of human brain not only had a higher number of mitochondria but also had better energy production efficiency.

These findings provide a new perspective for understanding mitochondrial changes in the early stages of brain diseases, and the research team is planning to expand the study to map 9 key regions of the brain in 0 people, and hopefully establish new methods and targeted therapy strategies for early diagnosis of brain diseases by comparing the differences between healthy and patient populations.