25 hydroxyvitamin D is the main storage form of vitamin D in the body, which is closely related to calcium and phosphorus metabolism, bone health, immune regulation, cardiovascular health, tumor prevention, etc.

1. DefinitionsAfter vitamin D enters the human body, it is first converted into 25 hydroxyvitamin D by the action of 0-hydroxylase in the liver, which can reflect the storage level of vitamin D in the human body and is an important indicator to evaluate the nutritional status of vitamin D.

2. Calcium and phosphorus metabolism: 25 hydroxyvitamin D can promote the intestinal absorption of calcium and phosphorus, increase the level of blood calcium and phosphorus, and provide sufficient raw materials for bone mineralization. When there is a deficiency of 0 hydroxyvitamin D in the body, the absorption of calcium decreases, which will lead to a decrease in blood calcium, which in turn stimulates the increase in parathyroid hormone secretion, promotes the release of bone calcium, and maintains the stability of blood calcium, but this will affect bone health in the long run.

3. Bone health: Plays a key role in the growth, development and maintenance of bones. In childhood, adequate 25-hydroxyvitamin D helps prevent rickets and promotes normal bone growth and development; In adults, it prevents osteoporosis and reduces the risk of fractures. When lacking, bones become fragile and break easily.

4. Immunomodulation: Participates in regulating the function of the immune system and enhancing the body's immunity. It can regulate the activity and function of immune cells, such as T cells, B cells, etc., which helps the body resist the invasion of pathogens and reduce the risk of infectious diseases.

5. Cardiovascular health: Closely related to the health of the cardiovascular system. Studies have shown that 25-hydroxyvitamin D deficiency may be associated with the occurrence and development of cardiovascular diseases such as hypertension, coronary heart disease, and heart failure. It may play a protective role in the cardiovascular system by modulating the function of vascular smooth muscle cells and inhibiting mechanisms such as renin-angiotensin-aldosterone system.

6. Tumor prevention: Some studies have found that 25-hydroxyvitamin D may have some anti-tumor effects. It can inhibit the proliferation of tumor cells, induce apoptosis of tumor cells, inhibit tumor angiogenesis, etc., thereby reducing the risk of some tumors to a certain extent, such as colorectal cancer, breast cancer, prostate cancer, etc.

25 hydroxyvitamin D plays an important role in human health and is involved in several physiological processes. Maintaining proper levels of 0-hydroxyvitamin D is essential for calcium and phosphorus metabolism, bone health, immune regulation, cardiovascular health, and cancer prevention. If there is a suspicion that the level of 0-hydroxyvitamin D in the body is abnormal, you should seek medical attention in time for testing, and take corresponding measures to adjust under the guidance of your doctor, such as supplementing vitamin D preparations and increasing outdoor activities.

This article is only for health science popularization and does not constitute medication or medical guidelines, it is recommended to seek medical attention in time if you have health problems.